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Randomised controlled trials, when appropriately designed and conducted, can produce robust evidence for the safety and efficacy of health or medical interventions. 

Compared with a classical fixed design, an adaptive design can render a trial more efficient and/or ethical.

Adaptive designs encompass diverse methods and can improve the efficiency of randomised controlled trials. However, the design and conduct of an adaptive trial is more complex than for a traditional fixed design, with specific expertise and infrastructure often required.

This MJA medical education shares more.

Learning Outcomes

1. Explain key components of the medical education
2. List main findings
3. Recognise the significant findings from the research.

Details

Authors: Elizabeth G Holliday, Natasha Weaver, Daniel Barker and Christopher Oldmeadow

Article Type: Medical education