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Updating the diagnosis and management of elevated serum ferritin levels in the era of routine ferritin testing of blood donors by Australian Red Cross Lifeblood

Description

Elevated serum ferritin levels (hyperferritinaemia) can reflect a wide range of conditions and are not solely indicative of iron overload. A thorough clinical assessment is required to identify serious causes of high serum ferritin levels, evaluate iron status and manage associated complications.

The upper limit of the reference interval for serum ferritin values varies between laboratories due to different testing methods, and the Royal College of Pathologists of Australasia no longer specifies upper limits in its guidance to laboratories. Up to 20% of men have elevated serum ferritin concentrations, while the prevalence in women varies from 3% in premenopausal women to 17% in women older than 70 years. Less than 10% of cases of hyperferritinaemia are due to iron overload.

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Details

Authors: Gary D Zhang, James Chen, Daniel M Johnstone, Martin B Delatycki, Katie Allen and John K Olynyk

Article Type: Medical Education

CPD Activity Details
Provider
MJA
Domain
Educational Activities
Type
General Learning
Activity
Professional reading
CPD Hours
0h : 30m
Topic
Haematologic Diseases
Audience
Medical practitioners
Applicable CAPE Aspects
_
Effective Year

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Accepted by

*Medical Board of Australia’s (MBA)’s revised Registration Standard: Continuing professional development (the Standard)