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PPS is prescribed to treat interstitial cystitis (also referred to as “bladder pain syndrome”). Interstitial cystitis is a complex multifactorial disorder with poorly understood pathophysiology. It has been described as pain perceived to be related to the bladder or pelvis accompanied by other urinary symptoms, such as urgency or frequency, not caused by an infection or other identifiable aetiology.

The estimated prevalence of interstitial cystitis is 1–3% of women and is less common in men by a factor of five to ten. Treatment of interstitial cystitis is challenging, as no single treatment is particularly effective. A multimodal approach to treatment is common and can include behavioural changes, pelvic floor exercises, stress reduction, oral medications (including tricyclic antidepressants, hydroxyzine, and PPS), and/or procedures such as intravesicular therapy with lidocaine.

This MJA medical education shares more. 

Learning Outcomes

1. Explain key components of the medical education
2. List main findings
3. Monitor patients taking PPS for PPM.

Details

Author: Aaron Priluck, Adrian T Fung and Mandeep S Singh

Article Type: Medical education